Description
Product Characteristics:
Subcellular location: Cell membrane
Synonyms: Cd210, CDw210b, CRF2 4, CRF2-4, CRFB4, Cytokine receptor class II, Cytokine receptor class II CRF2 4, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, Cytokine receptor family II member 4, D21S58, D21S66, I10R2_HUMAN, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10R2, IL-10RB, IL10R2, IL10RB, Interleukin 10 receptor beta, Interleukin-10 receptor subunit 2, Interleukin-10 receptor subunit beta.
Target Information: The protein encoded by this gene belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. This gene and three other interferon receptor genes, IFAR2, IFNAR1, and IFNGR2, form a class II cytokine receptor gene cluster located in a small region on chromosome 21. [provided by RefSeq, Jul 2008]